Quando se ingere o DMT por fumaça, ou seja, fumando, o DMT vai direto pro cérebro e rapidamente já acontece os seus efeitos. o DMT é uma triptamina muito parecida com a serotonina, por conta disso quando o DMT está no cérebro ele age diretamente nos receptores de serotonina, que é responsável pela a concentração e foco. quando o DMT é ingerido pelo o estomago, ele só vai causar efeito se junto com a bebida tiver uma planta que contenha uma IMAO (Inibidor de Monoamina oxidase).

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